Market Rasen & Louth will be on their guard this weekend when Loughborough make the trip to their Willingham-Road base on Saturday (2.15pm).
The Leicestershire side suffered a narrow one-point defeat to the Red & Greens earlier in the season and will be looking for revenge.
Rasen dropped a place below Loughborough following their 15-3 defeat at Midlands One East leaders Derby last Saturday.
The Red & Greens started well against their high-flying opponents, but were guilty of failing to make their possession count and were caught out with unforced errors.
Derby took the lead on 16 minutes. The hosts kicked a penalty deep into the Rasen twenty-two and secured the lineout allowing centre Ben Marlow to slice through some nondescript Rasen defending to open the scoring.
Winger Roome added the conversion to bring further joy to the home supporters.
Rasen were dealt a blow when captain Ollie Cole was injured and forced to miss the rest of the game.
Derby created one more chance before the half-time whistle, but Roome failed to cross the line.
Roome made amends after the restart.
Rasen conceded a penalty on their twenty-two and Roome stepped up to slot the kick home with the aid of an upright to give Derby the perfect start to the half.
However, Rasen kept up their competitiveness and three minutes later their hosts reciprocated giving full-back Meehal Grint his first kick at goal, which he landed with ease.
The tit for tat penalties continued as first Derby fell foul of the law at a five metre scrum when a poor pass had forced centre Paul Cook to concede the minor and then Rasen infringed.
The latter proved decisive as Derby kicked to touch and won the lineout to drive flanker Todd Bullions over the line for their second try.
Thereafter Derby became strangers to the Rasen twenty-two except for one occasion when they mounted a series of drives close to the Red & Green line before the ball popped out and the scavenging Chamberlin nabbed it to charge up field.
After the second Derby try Rasen had plenty of possession, but could not turn it into points.
For the second time this season Derby had realised they had been in a game, but their clinical finishing had won the day and left Rasen empty handed.
Rasen: C. Starling, Oliver, Cole, Mills, Thornes, Inman, Chamberlin, Murphy, A. Neesha, M. Neesham, Everton P, Jones, Cook, Harvey, Grint.
Subs: M. Starling (not used), Southwell (Cole).