Essential maintenance works will result in Thornbridge car park in Lincoln to be closed for up to five weeks.
The car park, located over the bus station and Co-op shopping centre in the city, will be shut to all traffic from February 11.
The City of Lincoln Council, which runs the car park, need to carry out important resurfacing works.
Steve Bird, the City of Lincoln Council's assistant director for communities and street scene, said: "While we appreciate this is a busy car park in the city centre, these works are vital, not only to ensure we maintain the integrity of the building, but for the continued operation of the shops below.
"The Council is investing in the order of £400,000 into upgrading the key areas of the car park's surface as we want people to be able to use Thornbridge safely.
"We are sorry for any temporary inconvenience this will cause, but investing money into this local car park will encourage people to continue to park local and shop local."
The bus station and shops below the car park will continue to operate as normal throughout the works, but the car park itself will be closed off for safety reasons.
The council will be working closely with shop owners based in the building to keep them informed of noise issues as the works proceed.
Leaflets will be given out to car park users at this site from today through to the Sunday before closure.
The leaflets advises motorists of the closure, and of alternative opportunities for parking including Broadgate and Tentercroft Street.
The Council will be posting regular updates on progress regarding this closure on its web site.