Student nurses will hone their skills in mocked-up medical suites.
Three rooms at the Think Tank business centre in Lincoln have been transformed to mimic different scenarios.
One is a pretend patient at home, another is a mocked-up GP surgery and the third is a replica hospital ward.
And the students will be able to simulate life-saving medical skills on hi-tech mannequins.
The University of Lincoln was awarded a contract to provide undergraduate nursing teaching in Lincolnshire last year. The contract has provided the funding for the new learning facilities.
The student intake has risen from 48 students to 220 this September, including the first intake of 34 mental health nurses.
Dianne Ramm, senior nursing lecturer and clinical skills lead, said: "Students will be acting as patients in some scenarios and they will get a perspective of treatment from the patients' point of view.
"It is vital student nurses can tell patients they have had experience of being in the hoists and other pieces of equipment to reduce the feeling of vulnerability."
Student nurses often become emotionally involved during simulation despite using dummies but Sean Morton, senior nursing lecturer is pleased the students experience these feelings.
"The emotional stress that goes through the students when working with a dummy is the same as if it was a real person," he said.
"That benefits the students because they can do what they think is right and then we can step back, switch everything off and discuss what could perhaps have been done differently."
The new facilities have been a hit with current students at the university.
Wendy Graham, a third year student, said: "Having the experience of working in these scenarios will give us more confidence when we go onto the wards on placements."