A multi-storey car park, a hotel and new shops are included in a multi-million pound plan which will transform Lincoln city centre.
New restaurants and major building projects are also part of the ten-year masterplan drawn up by the University of Lincoln.
The proposal, which will create hundreds of jobs, was handed to planners at the City of Lincoln Council this week.
It lays out how the city's Brayford Campus will grow over the coming years to benefit not just students but the city as a whole.
Other features include a new walkway linking the High Street and Brayford Wharf East, new academic buildings and student accommodation blocks and an access bridge over the rail crossing.
Professor Ieuan Owen, deputy vice-chancellor at the university, said: "The university has undergone extraordinary growth over the last decade, both in our facilities and in our standing among UK institutions of higher education.
"We're now recognised as one of the most vibrant and innovative universities in the country, and this masterplan document is an important component in our strategy to continue this upward trajectory."
Matt Corrigan, chief executive of the Lincoln Business Improvement Group, said: "The University of Lincoln is a vital part of the city and the new masterplan shows how it has matured into almost its own quarter within the city centre.
"I think the spread of activities towards High Street is to be welcomed and the continued investment in the university is also important.
"The university itself is still ongoing and there's still more investment to come – and that's the really exciting thing about it."
If every aspect of the masterplan goes ahead, it will add around 100,000 square feet to the campus.
Surveys have also been carried out to ensure cathedral views are protected, wildlife is preserved and traffic flow is unaffected.